X-linked disorders with cerebellar dysgenesis

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X-linked disorders with cerebellar dysgenesis

X-linked disorders with cerebellar dysgenesis (XLCD) are a genetically heterogeneous and clinically variable group of disorders in which the hallmark is a cerebellar defect (hypoplasia, atrophy or dysplasia) visible on brain imaging, caused by gene mutations or genomic imbalances on the X-chromosome. The neurological features of XLCD include hypotonia, developmental delay, intellectual disabili...

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ژورنال

عنوان ژورنال: Orphanet Journal of Rare Diseases

سال: 2011

ISSN: 1750-1172

DOI: 10.1186/1750-1172-6-24